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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @C_Reilly5 if AI is cooks for 100 years, we have robots traversing our veins, algorithms running our minds, the world running on a tapestry of intelligence that rivals our ability to understand, it's possible that things could change

    Sep 4, 2025 1 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    8/ Preclinical evidence for improved brain blood supply and flow

    In-vivo laser scanning microscopy was used to measure vascular function and blood flow in the cortex with rat brains treated with PEMF.

    Treated rats showed 10% increase in the diameter of brain microarteries

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    Sep 4, 2025 2 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/ Musculoskeletal pain and function in osteoarthritis patients

    A meta-analysis of 15 randomized placebo controlled trials in osteoarthritis patients show clinically meaningful short-term improvements in pain (-1 standard deviation reduction), stiffness (0.4 standard deviation),

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    Sep 4, 2025 2 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/ Bone health and fracture healing

    A meta-analysis with 14 studies and 1,131 participants showed that PEMF increased bone fracture healing rate by 22%, relieved pain (-0.5 Standard Deviations), and accelerated healing time (+1 Standard Deviations), in participants undergoing

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    Sep 4, 2025 2 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ Clinical and preclinical evidence supporting the expected benefits of PEMF

    Vascular function and blood pressure 12 weeks of PEMF therapy in adults with high blood pressure improved vasodilation measured as 2% meaningful increase in FMD, no increase with control.

    Meaningfully

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    Sep 4, 2025 3 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Sleep quality and autonomic tone

    101 participants with diagnosed insomnia underwent a 4-week randomized placebo controlled double-blinded trial with PEMF, the intervention group showed multiple improvements versus placebo.

    70% of patients on PEMF experienced partial or

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    Sep 4, 2025 2 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ How I am measuring efficacy and benefits:

    Vascular health
    + Advanced Central Blood Pressure measurements
    + Molecular markers: VEGF, MMP-9

    Microcirculation and muscle blood flow during exercise
    + Moxy muscle oxygen monitor.

    Sleep and autonomic balance
    + Sleep architecture,

    Sep 4, 2025 4 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Key molecular and cellular mechanisms of PEMF benefits
    Nitric-oxide (NO) mediated vasodilation: PEMF activates endothelial nitric oxide synthase by activating the ion channels in cellular membranes and triggering calcium influx into the cells, raising NO levels in the

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    Sep 4, 2025 3 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    0/ What is PEMF? (Pulsed Electromagnetic Field)

    A therapy that uses pulsed magnetic fields to stimulate the body at the cellular level. Research shows it can improve blood flow, oxygen delivery, vascular function, sleep, bone health, and recovery. This happens in part through

    Sep 4, 2025 4 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1/ My protocol

    Device: Pulse XL Pro PEMF
    We are using solid-state, 2 accessory ports with separate controls for Magnetic Field Strength (MFS), Pulses-Per-Second (PPS; frequency), and 19 pulse-rate settings.

    This device lets us run a whole-body accessory and a focus accessory at

    Sep 4, 2025 4 0 View on X
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