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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    8/
    Hyperbaric Oxygen Oxygen Therapy (HBOT) We completed a fairly extensive literature search and concluded there is supporting evidence for its usage for acute therapies but there was insufficient evidence to use it for our objective of biological aging. (cont'd)

    May 4, 2023 55 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    9/ The evidence for telomere elongation and senescent cells didn’t cross our thresholds to implement into our protocol.

    May 4, 2023 56 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/
    Is a sauna part of your protocol? We don’t currently have a sauna protocol as part of Blueprint, not because there aren’t potential benefits, but because we haven’t been able to identify evidence that supports our objective of reducing biological aging for me.

    May 4, 2023 53 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/
    Do you get sun exposure? Yes, a little but not too much.  A little can increase dopamine & nitric oxide but too much will cause skin aging.

    May 4, 2023 66 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/
    +40% liver markers improvement (avg sum ALT+AST+GGT = 49)

    May 4, 2023 29 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/
    FAQs
    Is cold therapy part of the protocol? We don’t currently have a cold therapy protocol as part of Blueprint, not because there aren’t potential benefits, but because we haven’t been able to identify evidence that supports our objective of reducing biological aging for me

    May 4, 2023 49 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/
    + Grey hair age reduced from age 70 to 41 in 6 months
    + Short Chain Fatty Acids are suboptimal
    + For the people: NR vs NMN 180 day trial results: both worked to get my intracellular NAD to level age 16 equivalent (recent 54.6μM)
    + Eye exam results (+ therapy for my dry eye)

    May 4, 2023 104 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/
    + New therapies: HGH for thymus rejuvenation & 17aE2, non feminizing estradiol (Rx), based upon male longevity evidence.
    + 3T MRI scan showed I have perfect liver fat, iron & stiffness.  My liver fat is 1.36%, top 10% of ppl. < 5% is the normal range for non-fatty liver.

    May 4, 2023 36 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Blueprint 4/23 field reports:
    + 20 yr bio age equivalent reduction in Free Testosterone Index (FTI)
    + 2 month streak of 100% sleep performance
    + 12 year age reversal in 500 day average HRV
    🧵
    Full details:

    Tweet media
    May 4, 2023 453 29 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    For those just tuning in, come play.

    A 7 day challenge to avoid these🧟‍♂️SAD🧟‍♂️behaviors:

    1. eat too much food
    2. consume junk food
    3. miss bedtime
    4. skip exercise

    1 point for each above
    Zero is best score
    Like if ur playing
    Share score if u want

    May 4, 2023 113 6 View on X
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