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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    If you recently got less than four hours of sleep, I have some news for you.

    Apr 30, 2025 3550 255 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Protocol for optimal sperm health:

    + Sleep: 8+ hours nightly
    + Reduce inflammation: omega-3s, NAC, exercise
    + Avoid testicular heat: no saunas (or sauna with an testicular ice pack), tight underwear, or laptops
    + Eliminate toxins: alcohol, cigarettes, plastics
    + Train hard:…

    Apr 30, 2025 304 18 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Semen quality isn’t just about reproduction. It’s one of the clearest biomarkers of systemic aging: tightly linked to hormone health, inflammation, mitochondrial function, and metabolic fitness.

    Across five lab tests in 3 months, my total motile sperm count (TMC) averaged 165…

    Apr 30, 2025 131 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    While global sperm health is plummeting, my sperm count is over 4× the average. At age 47.

    Global data from 1973 to 2018:
    + sperm concentration declined by 51%
    + total sperm count declined 55%

    My sperm concentration (143 million) and count (380 million) both exceed 1973 levels…

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    Apr 30, 2025 791 29 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Lift weights and get jacked.
    Sleep well and stabilize your mood.
    Eat well and feel energized.

    Apr 30, 2025 5637 363 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    8/ The Rejuvenation Olympics enables anyone to compete to determine who can achieve the lowest speed of aging. I am currently #1 in the world out of 6,000 participants.

    To qualify, you need to complete three tests within two years. Your average is then used for the leaderboard.…

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    Apr 30, 2025 90 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/ Here are more details on the history and generations of pan-tissue epigenetic clocks, and how PACE came to be.

    PACE is a 3rd generation pan-tissue clock.

    Pan-tissue epigenetic clocks aim to provide a comprehensive assessment of an individual’s biological age or the rate at…

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    Apr 30, 2025 32 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/ As far as I know, I've used this speed of aging measurement more than anyone one the world. In the last 12 months alone I've measured myself 22 times.

    My team and I choose this frequency of measurement because we find the data uniquely insightful to measure the effect of…

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    Apr 30, 2025 63 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Internally PACE has gained our trust by validating what we learned via years of rigorous biomarker testing.

    Here are examples of how PACE results retrospectively aligned with our strategic decisions:

    + Rapamycin cessation: We stopped my rapamycin protocol due to observed…

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    Apr 30, 2025 44 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ PACE aces every benchmark

    According to recent pre-prints and previous research, the PACE biological aging clock demonstrates strong reliability:

    + It accurately detects an increased speed of aging following interventions known to accelerate aging, such as chemotherapy and…

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    Apr 30, 2025 38 0 View on X
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