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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ Sources
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    Nov 21, 2024 393 6 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2.ii/ Imbalance between Omega6/Omega3 intake

    In ancient and blue zone diets, Omega6/Omega3 ratio was close to 1:1. Due to the lack of fish and other Omega3 sources in modern diets, and the overabundance of plant seed oils this balance has shifted to 15:1 Ref (20)

    Omega3 fats…

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    Nov 21, 2024 268 12 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2.iii/ Palm oil and cancer risk

    Preclinical evidence emerged of palmitic acid, the principal component of palm oil, leading to increased metastasis in mouse cancer models, as well as increasing the susceptibility to induced breast cancer in rats. Ref (24) Ref (25)

    The evidence…

    Nov 21, 2024 199 8 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2.i/ Bad cooking practices: overheating, reheating, and over consumption of deep fried food.

    One serving of deep fried food a day increases all-cause and cardiovascular mortality risk by 8%. And only one weekly serving of fried chicken is enough to increase the risk to 13%. Ref…

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    Nov 21, 2024 443 28 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1.v/ Claim: Seed oils consumption increases cancer risk

    Rebuttle
    A meta-analysis with over 150,000 total participants showed no significant effect of vegetable oil intake on breast cancer risk, while olive oil was associated with a protective effect. Moreover, the general trend…

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    Nov 21, 2024 197 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ The big question; Why do such unfounded claims and misconceptions linger around cooking plant oils?

    It is not about vegetable seed oils, it is about their context and use in modern diets.

    i. Cooking: Overheating oils and fats in general (as in deep frying)
    ii. Lack of…

    Nov 21, 2024 406 19 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1.iii / Claim: seed oils cause inflammation

    Rebuttal: A meta-analysis showed that Linoleic Acid (the major Omega6 precursor in seed oils) consumption had no effect on inflammatory markers in the blood. Ref (7)

    Linoleic acid, the principle Omega6 PUFA in vegetable seed oils,…

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    Nov 21, 2024 222 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1.iv/ Claim: seed oils consumption increases diabetes risk

    Rebuttal: a randomized controlled trial with 141 type-2 diabetes patients showed that a low-gylcemic diet rich in canola oil was associated with a greater HbA1C reduction (long term blood sugar marker) than a…

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    Nov 21, 2024 198 5 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1.i/ Claim: seed oils accelerate aging, cause premature death

    Rebuttal:
    Linoleic acid is the primary fatty acid in plant seed oils and it is a precursor for Omega6 PUFAs that make up 20% of the lipids in cellular membranes Ref (1).

    A large study with over 500,000 American…

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    Nov 21, 2024 404 13 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1.ii/ Claim: seed oils increase blood cholesterol and cardiovascular disease risk.

    Rebuttal: Replacing animal fat with plant seed oil also reduced mortality risk due to heart disease according to the same study with 500,000 participants Ref. (2)
    A meta-analysis also reported…

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    Nov 21, 2024 296 6 View on X
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