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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ Brain health

    28.6% reduction (from 0.14 to 0.1 pg/mL) in the brain damage and dementia marker pTAU127.

    The phosphoprotein p-TAU217 is a specific marker for Alzheimer disease, with levels higher than 0.18pg/mL potentially indicative of plaque accumulation in the brain, hence…

    Mar 18, 2025 165 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Skin

    + my facial skin got 1 year younger (Pre-HBOT: 39 years→ Post-HBOT: 38 years)
    + major improvement in UV spots score  (55th→ 68th percentile)

    Indicative of significant removal of Advanced Glycation End-products AGEs from the skin, ostensibly due to improved…

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    Mar 18, 2025 156 6 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Microbiome

    Dramatic improvements in my microbiome:

    + Akkermansia muciniphila increased by 1,000%.
    Pre-HBOT: Not detectable → Post-HBOT: 4.2E4 CFU/g

    Akkermansia is linked to gut barrier integrity and metabolic health.

    Note, I started Akkermansia on August 9th and two…

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    Mar 18, 2025 154 8 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1/ Vascularization

    300% increase in VEGF drives the formation of new blood vessels which improves tissue perfusion and oxidation, essential for improving fitness, physical and cognitive performance . Also has further pro-longevity effects on gene expression.

    Improved muscle…

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    Mar 18, 2025 180 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ Telomeres

    Telomerase activity of a 12 year-old (7.7%). Telomers keep chromosomes from falling apart. They are essential for healthy cell division, including stem cell renewal. As we age, cells lose their telomerase activity and telomeres get shorter, when telomeres are too…

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    Mar 18, 2025 171 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    HBOT ranks as one of the highest value health therapies I’ve done. Results from 60 sessions:

    + wiped out all systematic inflammation in my body. Below detectable levels. This is wild.
    + 300% increase in VEGF (formation of new blood vessels)
    + telomerase activity of a 12 year…

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    Mar 18, 2025 5552 319 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    0/ Inflammation

    Post HBOT, there’s no detectable systemic inflammation in my body (hsCRP). Inflammation is the foundation of disease and all things bad health.  Before HBOT, my inflammation markers were in the top 5% of 18-29 year olds (you get more inflamed as you age).

    HBOT…

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    Mar 18, 2025 324 12 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @Tonyyjabroni two bananas before bed will raise your resting heart rate by 5-10 bpm, delay sleep onset by 15-30 minutes, result in a mid-night awakening due to the glucose crash, and you'll lose about 10% sleep efficiency. So you won't die but you won't feel rested in the am.

    Mar 18, 2025 132 3 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @danestephyoo it's always me posting

    Mar 18, 2025 109 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    I see what you're up to
    stop scrolling
    put the food away
    get off the couch
    go to bed

    Mar 18, 2025 4313 112 View on X
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