@0xadot that I can get on board with. If you're gonna do something, get after it.

@cs_olen I'm building around Immortalism now.

Friends, stop drinking alcohol.

Not cut back. Eliminate.

> alcohol increases cortisol
> disrupts REM sleep
> accelerates epigenetic aging
> shrinks hippocampal volume
> elevates resting heart rate
> raises inflammatory markers
> impairs glucose metabolism for 16 hrs

One

@AutismCapital We're trying to figure out the next move. Whether we re-dose 5, return to psilocybin, try something else, or pause. The data we're getting is really interesting. No one has interrogated these molecules with high fidelity measurement so all intuitions are guesswork.

5-MeO-DMT gave me a single idea that won't leave.

Our minds are not naturally capable of understanding the preciousness of our existence.

Not "life is precious" as printed on a poster. It's something much more specific. That the hardware we're running, human consciousness,

Sometimes I wonder if I've just built the world's most sophisticated way to avoid sitting in a room with nothing to measure.

Kate is reading next to me.

She's taking 15 breaths per minute and her heart rate is 64.

I didn't need an instrument to tell me this. I just know.

12 hrs of focused work yesterday. Surprised by the level of cognitive and mood lift.

Context switching 300x/day creates a noise floor of attention reside and chronic nervous system arousal. Microdosing cortisol.

Extended focus resensitizes, making the world interesting again

The totality of evidence does not support the conclusion that dietary erythritol drives cardiovascular harm.

The paper referenced claims erythritol “adversely affects brain microvascular endothelial cell function,” but it’s an in VITRO study bathing isolated cells in erythritol

@micsolana that seems on point