Skip to content
POSTS
  • POSTS
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Semen quality isn’t just about reproduction. It’s one of the clearest biomarkers of systemic aging: tightly linked to hormone health, inflammation, mitochondrial function, and metabolic fitness.

    Across five lab tests in 3 months, my total motile sperm count (TMC) averaged 165…

    Apr 30, 2025 131 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    While global sperm health is plummeting, my sperm count is over 4× the average. At age 47.

    Global data from 1973 to 2018:
    + sperm concentration declined by 51%
    + total sperm count declined 55%

    My sperm concentration (143 million) and count (380 million) both exceed 1973 levels…

    Tweet media
    Apr 30, 2025 791 29 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Lift weights and get jacked.
    Sleep well and stabilize your mood.
    Eat well and feel energized.

    Apr 30, 2025 5637 363 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    8/ The Rejuvenation Olympics enables anyone to compete to determine who can achieve the lowest speed of aging. I am currently #1 in the world out of 6,000 participants.

    To qualify, you need to complete three tests within two years. Your average is then used for the leaderboard.…

    Tweet media
    Apr 30, 2025 90 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/ Here are more details on the history and generations of pan-tissue epigenetic clocks, and how PACE came to be.

    PACE is a 3rd generation pan-tissue clock.

    Pan-tissue epigenetic clocks aim to provide a comprehensive assessment of an individual’s biological age or the rate at…

    Tweet media
    Apr 30, 2025 32 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/ As far as I know, I've used this speed of aging measurement more than anyone one the world. In the last 12 months alone I've measured myself 22 times.

    My team and I choose this frequency of measurement because we find the data uniquely insightful to measure the effect of…

    Tweet media
    Apr 30, 2025 63 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Internally PACE has gained our trust by validating what we learned via years of rigorous biomarker testing.

    Here are examples of how PACE results retrospectively aligned with our strategic decisions:

    + Rapamycin cessation: We stopped my rapamycin protocol due to observed…

    Tweet media
    Apr 30, 2025 44 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ PACE aces every benchmark

    According to recent pre-prints and previous research, the PACE biological aging clock demonstrates strong reliability:

    + It accurately detects an increased speed of aging following interventions known to accelerate aging, such as chemotherapy and…

    Tweet media
    Apr 30, 2025 38 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ How Biological Aging clocks gained a bad reputation

    The early adoption of epigenetic aging clocks inadvertently led to a body of literature containing inconsistent and conflicting biological age measurements across various interventions.

    This was largely because earlier…

    Tweet media
    Apr 30, 2025 35 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Two new pre-prints take a new approach to restore confidence to the field.

    A research team at Yale supported by TruDiagnostic is working to standardize the emerging field of epigenetic biological aging. To reliably benchmark and compare epigenetic aging clocks for assessing…

    Tweet media
    Apr 30, 2025 35 0 View on X
  • Posts navigation

    • «
    • 1
    • …
    • 69
    • 70
    • 71
    • 72
    • 73
    • …
    • 1,326
    • »
    © 2025 Bryan Johnson