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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    16/ In conclusion

    A lot of the evidence converges that red meat consumption reduces life expectancy and increases the risk of age related disease. Processing and overcooking makes red meat much worse for your health. And genetic predispositions can make it dangerous for you to…

    Jan 16, 2025 406 13 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    13/ Factors and contexts that can make red consumption meat beneficial

    Rich and highly bioavailable nutrient profile help prevent nutrient deficiencies

    Prevention of Vitamin B12 deficiency a study in 58 omnivorous healthy adults (18-60 years of age) showed that 1-month of a…

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    Jan 16, 2025 146 4 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    14/ Supports muscle gains in the elderly

    Gaining and retaining muscle mass gets tougher with age. In fact muscle mass starts declining 3-8% per decade between the age of 30-40, at the age of 60 the decline accelerates, on average.

    Meat with its easy to absorb universal amino…

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    Jan 16, 2025 148 5 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    12/ Susceptibility to late-onset autoimmune diabetes

    Major histocompatibility complexes play a crucial role in the immune system's ability to define the body’s own healthy cells from outside "invaders", people with high-risk genotypes of the HLA-DBQ1 and HLA-DRB1 are at an…

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    Jan 16, 2025 187 6 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    10/ Genes that make you especially susceptible to red meat damage and disease risk.

    While population level studies indicate the higher risk related to red meat consumption, your predisposition to this risk is not equal across the population and is affected - among other things…

    Jan 16, 2025 192 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    11/ Susceptibility to colon cancer

    Mutations “polymorphisms” that affect DNA repair and maintenance genes including XBA XBC and MSH3, arachidonic acid metabolism and associated inflammation pathways including PTGS2, anti-inflammatory transcription factors like NFKB1 all increase…

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    Jan 16, 2025 194 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    8/ Mechanisms of harm linked to red meat

    Various chemicals in red meat contribute to its damaging effects on the human body, these include the heme-iron (organic iron), which causes oxidative damage, inflammation and DNA damage. Furthermore, mutagenic nitroso compounds are…

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    Jan 16, 2025 270 10 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    9/ You don’t necessarily need red meat to grow muscles

    I am plant based. The only animal product I consume is my collagen-peptide supplement (25g/day), and my data shows that you can build muscle, optimize your body composition to be among the top 0.1% and your athletic…

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    Jan 16, 2025 387 19 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/ Cognitive Decline

    A fresh prospective cohort study of 133,771 participants found that higher processed red meat intake (≥0.25 servings/day) was linked to a 13% higher risk of dementia, 14% higher risk of subjective cognitive decline (SCD), and faster cognitive aging.…

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    Jan 16, 2025 258 13 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Cardiovascular disease

    A meta-analysis involving 4,462,810 total participants reported an 11% increase in cardiovascular disease risk for every additional 100g daily consumption of unprocessed red meat, and 26% higher risk for every additional 50g of average daily consumption…

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    Jan 16, 2025 276 15 View on X
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