I gave that motherfucker @hubermanlab a call

New muscle growth and preservation target identified in mice, potential target for muscle preservation with weight-loss medications and interventions

1. The study identified BCL6, a pro-cell-survival transcriptional factor, as a coordinator between nutrient availability and…

From the LA fires, there is unknown risk for toxins in the air, soil and water. We're going to try and quantify toxin levels. Please reach out if you have measurement capabilities and would like to help out.

team at bryan johnson dot com

People hate and that’s fine.
But credibility, that’s worth fighting for.

It doesn't matter if Taleb thinks poorly of me:  "...disgust I have for your brand…". He's written great books that I value even if he's prickly.

Some dismissed my single-rep leg press because it didn’t…

4/ I followed the instructions based on the peer reviewed literature. Based on this, my 1 rep maximum weight is 850 lbs, for my bodyweight of 171 lbs, so I am able to press 4.97 my bodyweight, putting my way beyond the 90th percentile for men between 20-29 of age, at 2.27…

2/ The maximum neuromuscular engagement for inclined leg press is achieved at 90°, 60°-70° for squats.

3/ Slower, controlled movements give the best results, as they lead to increased muscle protein synthesis rates compared to faster movements

0/ Here is the standardized data by age.

Weight pushed per bodyweight = 1RM leg press/ bodyweight

1/ The instructions and standards for doing a perfect leg press are well addressed and documented in peer-reviewed studies. For 5RM leg press the time gate to measure speed was set at 90° knee angle, considered the cut-off for achieving a repetition in this exercise.