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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @nic__carter the night time erection data is legitimate. Read the thread, it has the science. Cialis is not responsible for my nighttime erections because studies show it has no significant effect on nocturnal erection duration in healthy men; its primary benefit is in restoring normal…

    Mar 25, 2025 182 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @boneGPT Read the thread. Cialis is not responsible for my nighttime erections because studies show it has no significant effect on nocturnal erection duration in healthy men; its primary benefit is in restoring normal erectile function in those with ED.

    Mar 25, 2025 117 0 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    7/ Never mix Cialis (or any ED pill) with nitrate heart meds (e.g. nitroglycerin)​

    That combo can cause a dangerous blood pressure crash. Also be careful if you're on multiple BP meds or have very low BP. Always consult your doctor first.

    A study comparing 55,777 men treated…

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    Mar 25, 2025 365 10 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Cialis can boost your brain

    Better blood flow might aid cognitive functions too, especially as we get older.

    In a small trial, older men taking daily Cialis improved on cognitive tests of attention and processing speed​. Even their brainwave patterns (EEG) got sharper,…

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    Mar 25, 2025 306 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/ Long term Cialis use is generally safe in men, but comes with some possible side effects

    Tadalafil is a prescription drug. Common side effects at low doses: headache, flushing, nasal congestion, or heartburn – usually mild. It's considered safe for long-term use in many men…

    Mar 25, 2025 267 3 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Cialis can improve your metabolism, blood sugar control and can help increase fat burning.

    Daily Cialis might improve how our bodies handle sugar. In a 2022 trial with diabetic men, 5 mg/day modestly lowered HbA1c (blood sugar marker) over 6 months​, Suggesting better insulin…

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    Mar 25, 2025 359 5 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ Cialis reduced chronic inflammation, a major driver of aging

    Termed “inflammaging”, chronic inflammation speeds aging. In a small study, men on daily Cialis for 6 months saw their elevated inflammatory markers (e.g. IL-6) drop back to normal​A calmer immune system = a…

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    Mar 25, 2025 350 6 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1/ My nighttime erections are better than the average 18 year old, but Cialis is unlikely to play a meaningful role in them or even my sexual function.

    While it’s true that daily low-dose Cialis (2.5–5 mg) can help men with erectile dysfunction (ED) or benign prostatic…

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    Mar 25, 2025 403 7 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ Here is why you may consider taking Cialis

    Cialis’s effects on blood vessels might benefit many organs. It boosts nitric oxide (NO), relaxing arteries.

    Enabling better circulation, organ blood flow, and a bit lower blood pressure. Basically helping to keep your blood…

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    Mar 25, 2025 491 19 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    I take 2.5 mg of Cialis daily.
    Not for erections, but for longevity.

    Here’s what the science says about Cialis and lifespan extension…

    And why it’s not the reason behind my 3 hour long titanic nighttime erections.
    🧵

    Mar 25, 2025 8555 436 View on X
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