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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ I founded Kernel in 2015 because I thought it pairing the human mind with AI was going to be really important to the future.

    Then, when becoming the most biologically measured person in history (Blueprint + Don’t Die), I discovered that getting high quality, functional brain…

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    Feb 18, 2025 947 32 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ The early data is impressive.

    Flow measurements of brain function in response to cognitive and emotional stimuli have been shown to predict with 90% accuracy if a patient will respond to treatment from depression before they have their first dose.

    Feb 18, 2025 700 9 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    6/ If you're interested in brain health, you can now join one of two clinical trials:

    1) Healthy aging - Kernel has distinguished normal cognitive changes from early disease signs using brain activity patterns.

    Kernel Flow is a promising tool to detect mild cognitive…

    Feb 18, 2025 673 17 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Normally it would be hard and next to impossible to get this kind of high fidelity brain data, but it was made easy with Kernel Flow.

    Flow is the non-invasive brain interface technology I dedicated seven years of my life building (and personally investing $64 million). The…

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    Feb 18, 2025 975 28 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1/ After three days, my previous patterns started to take hold again, closing what many refer to as the "therapeutic window” that opens post a ketamine or psychedelic administration.

    Top images: Baseline measurements of my brain 5 days prior to receiving ketamine.

    Bottom…

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    Feb 18, 2025 746 19 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ This image shows my functional connectivity (traffic patterns) was stable for days 1-5 prior to ketamine and showed large changes during the ketamine session. Post Ketamine, my functional connectivity decreases for days and then begins trending to normalize back to his…

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    Feb 18, 2025 640 15 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    I injected the horse tranquilizer Ketamine and tracked my brain data for 15 days. It completely scrambled my brain.

    In a world-first we answered the question ‘what happens to the brain before, during, and after ketamine treatment?’ We also discovered how long it took for my…

    Feb 18, 2025 17492 1084 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    0/ Before taking ketamine, my brain activity followed fixed, predictable patterns, as observed over 10 days of measurement. Imagine the brain as a global air traffic network, where each airport (or brain region) has consistent flight routes and traffic volumes—like the steady…

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    Feb 18, 2025 1330 52 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    Your phone and social media has your addicted. They do not have your best interest in mind. It puppets your thoughts, emotions and desires.

    Be a high agency person and fight back. Turn your phone off 30 minutes before bed. Do not let it interfere with restful sleep.

    Feb 18, 2025 4333 288 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    44 bpm was my resting heart rate just before doing to sleep last night. It gave me a perfect night's sleep.

    If you can only optimize one thing in your life, focus on your resting heart rate. Nothing influences my sleep quality more than RHR.

    How to lower RHR:
    + Final meal of…

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    Feb 18, 2025 3363 160 View on X
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