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  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    4/ Metabolites from other sources

    2,4-Dichlorophenoxyacetic Acid (2,4-D), which surged from undetectable at baseline to beyond 95th percentile following the fires. While this is a herbicide metabolite is unlikely to be produced by the burning of trees or houses, it is likely to…

    Feb 28, 2025 46 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    5/ Potential links to my exposure to air pollution in India

    While both the timing and composition of the toxic metabolites in my panel indicate a very likely acute spike linked to the urban wildfire (especially fumes and ash from burning homes) in LA, a contribution of my…

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    Feb 28, 2025 63 5 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    2/ Phthalate metabolites

    Phthalates are commonly used plasticizers (additives to make plastic more flexible), markedly increased due to homes burning in wildfires.

    Phthalates and their metabolites are endocrine disruptors, which are linked to reproductive, developmental,…

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    Feb 28, 2025 77 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    3/ Volatile organic compounds (VOCs) metabolites

    As the name implies, these are common toxins in the fumes of burning organic materials, including wildfires. Dioxins, polycyclic aromatic carbons PACs, benzene, and xylene are common examples. Most of these compounds cause…

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    Feb 28, 2025 62 1 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    0/ I suppose if there was one person in LA who was routinely measuring their toxin levels when the fires broke out, it would be me.

    My urinary toxins panel taken at the height of the LA wildfires on January 28th, 2025 showed 9 acutely increased metabolite toxins (4 of which…

    Feb 28, 2025 214 6 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    1/ Almost all the elevated toxic metabolites come from exposure to the fumes of burning plastics and synthetics from homes, rather than burning trees in the wildfire itself.

    The acutely elevated toxic metabolites in my urine sample from January 28th, 2025 can be categorized in…

    Feb 28, 2025 119 2 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    The LA fires filled my body with harmful toxins.

    One toxic chemical, NAPR, an organic solvent used in metal cleaning, foam gluing, and dry cleaning, increased by 728%.

    If you were exposed too, here is what you can do. 🧵

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    Feb 28, 2025 2774 193 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    @anothercohen Testosterone levels naturally decline ~1% per year after age 30-40 however many men over 40, including myself, naturally maintain healthy levels of testosterone via strength training, cardio, sleep, and nutrition.

    Feb 28, 2025 1618 22 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    The Kardashians and @hubermanlab came over for dinner.

    We discussed if we may be the first generation to not die. @KimKardashian was down. @khloekardashian wasn't sold. On @hulu tonight.

    Feb 27, 2025 1379 39 View on X
  • Bryan Johnson
    Bryan Johnson @bryan_johnson

    The Kardashians and @hubermanlab came over dinner.

    We discussed if we may be the first generation to not die. @KimKardashian was down. @khloekardashian wasn't sold. On @hulu tonight.

    Feb 27, 2025 87 4 View on X
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